Stem Cell Therapy For Endometrial

The endometrium has progenitor stem cells that can replace all of the endometrium during each menstrual cycle.

Stem cell therapy for endometrial.

Role of the wnt ctnnb1 pathway was published in the journal stem cell reports. 0 reprogramming a type of patient derived stem cell to produce healthy uterine cells called endometrial stromal fibroblasts may be a potential treatment for endometrial diseases such as endometriosis a study suggests. Preclinical and clinical studies dem. Mscs gain a lot of attention for cell based therapy due to their characteristics including differ entiation ability and immunomodulatory effect.

Mesenchymal stem cells are a promising candidate for cell based targeted therapies because they have characteristics such as self renewal multipotency low immunogenicity and non oncogenicity. Stem cells exhibit unique characteristics of self renewal and differentiation potential. However only the uses of mscs for treatment of endometrial infertility are highlighted in the present review. Mesenchymal stem cells mscs can be derived from several tissues such as bone marrow placenta adipose tissue or endometrial tissue.

It has the capacity to migrate to sites of inflammation including in endometrial lesions and tumor. Recruitment of stem cells from outside of the uterus occurs in setting of increased demand such as ischemia or injury. Recently cell therapy using stem cells becomes a novel treatment for several diseases including infertility. Currently there is massive interest in stem cells as a novel treatment method for regenerative medicine and more specifically for the regeneration of human endometrium disorder like asherman syndrome as and thin endometrium.