Radiation Therapy For Metastatic Renal Cell Carcinoma

Traditionally renal cell carcinoma rcc has been considered a radioresistant tumor and therefore radiation therapy rt was mainly confined in treatment of metastasis.

Radiation therapy for metastatic renal cell carcinoma.

Radiation therapy in the treatment of metastatic renal cell carcinoma. External radiation therapy uses a machine outside the body to send radiation toward the area of the body with cancer. Adenocarcinoma of the kidney is an unusual tumor both in its biological behavior and in its response to radiation treatment. Whereas stereotactic body radiation therapy sbrt involves radiation dose intensification via escalation we hypothesize sbrt might result in similar high local control rates as previously published on metastases of varying histologies.

Often rcc has no initial symptoms. Radiation is sometimes used to treat kidney cancer if a person is not healthy enough to have surgery or has only one kidney. Stereotactic radiosurgery and stereotactic body radiation therapy sbrt have led to a resurgence of the use of radiotherapy in the management of advanced renal cell carcinoma rcc. Radiation therapy uses high energy rays or particles to kill cancer cells.

Cancer is harder to treat after it spreads but. Sometimes other treatments will be tried first instead. External radiation therapy is used to treat renal cell cancer and may also be used as palliative therapy to relieve symptoms and improve quality of life. New advances in rt techniques including stereotactic irradiation have made encouraging contributions in the oncologic scenario opening up new opportunities in rcc management.

Onufrey v mohiuddin m. When symptoms and signs appear they include constant back pain fatigue anemia weight loss intermittent fevers a lump on the lower back side and blood in the urine. If the tumor and metastasis can be isolated surgical removal of the cancerous tissue and or treatment of the metastatic tumor by removal or other procedures such as stereotactic body radiation. These techniques provide excellent local control and palliation of metastatic sites of disease with minimal toxicity.

It s also called stage iv renal cell cancer. Renal cell carcinoma rcc is a type of kidney cancer. Melanoma and renal cell carcinoma rcc are traditionally considered less radioresponsive than other histologies.